Crystal Mackall
Crystal Mackall is the Ernest and Amelia Gallo Family Professor of Pediatrics and Medicine at Stanford University, the Founding Director of the Stanford Center for Cancer Cell Therapy, Director of the Parker Institute for Cancer Immunotherapy @ Stanford, and Associate Director of the Stanford Cancer Institute. During a career spanning more than three decades, she has led an internationally recognized translational research program focused on immuneoncology. Her work has advanced understanding of fundamental immunology and translated this understanding for treatment of human disease with a major focus on children’s cancers. Her group was among the first to demonstrate activity of CD19-CAR in pediatric leukemia, developed a CD22-CAR that has received Breakthrough Therapy Designations in pediatric B-ALL and adult LBCL, and is leading development of GD2-CAR T cells for diffuse midline gliomas, incurable brain tumors of childhood. Her group has also defined major resistance mechanisms to engineered cell therapies, and created numerous potency enhancements to overcome resistance. She has received numerous awards, including election as a member of the National Academy of Medicine, the American Association of Physicians, and the American Society of Clinical Investigation, and she is a Fellow of the AACR Academy and the Academy of Immunooncology. She is Board Certified in Pediatrics, Pediatric Hematology-Oncology and Internal Medicine, has co-founded 4 biotech companies, published over 250 manuscripts and filed more than 35 patents.
Abstracts this author is presenting: